Correlation of shear wave elastography Young's modulus with different clinical manifestations of Hashimoto's thyroiditis

QIANGYe; HUJian-qun; YIN Li-ping; WANG Jian-xiang; SONGXu-guang; WUYi-yun

Abstract：Objective To investigate shear wave elastography Young's modulus and correlation Hashimoto's thyroiditis (HT) with different clinical manifestations .Methods We divided the 86 cases ,which were clinically diagnosed with HT according to the thyroid function ,into the hyperthyroidism group ,the normal thyroid function group ,the subclinical hy‐pothyroidism group ,and the clinical hypothyroidism group .Using ultrasonic shear wave elastography ,we tested each group to get a elastic modulus .Using analysis of variance ,we compared the relationship of each group’s elastic modulus result .Results The elastic modulus of each group increased successively in hyperthyroidism group ,the normal thyroid function group ,subclinical hypothyroidism group and the clinical hypothyroidism group ,which were seperately (15 .543 ± 4 .319) kPa ,(20.083 ± 5 .444) kPa ,(26 .682 ± 5 .676) kPa ,(29 .210 ± 8 .848) kPa .There were significant differences be‐tween groups .( F=14 .925 ,P <0 .01) .The elastic modulus in hyperthyroidism group was lower than the normal thy‐roid function group ,the subclinical hypothyroidism group and the clinical hypothyroidism group .The differences were sta‐tistically significant ( P <0 .05) .The elastic modulus in the normal thyroid function group was lower than the subclinical hypothyroidism group and the clinical hypothyroidism group .The differences were statistically significant ( P < 0 .05) . Conclusion The shear wave elastography Young's modulus have some relevance ,with the clinical manifestations in differ‐ent periods of Hashimoto's thyroiditis ,which can provide a reference for the treatment of HT .