The application value of MRI in hypothalamic hamartoma classification

LIANGYi; LIZhen; TAOJing-xiong; WANG Jia; DUBo-lin

Abstract：Objective To discuss the application value of MRI in the hypothalamus hamartoma classification .Methods We collected the clinical data and MR imaging data of hypothalamic hamartoma of 6 patients from our hospital ,and com‐bined the literature to review .Results The hypothalamus hamartoma was diagnosed and divided into four categories (type I~ IV) ,the type I and type II hamartoma were located in the following position of hypothalamus and interpeduncular cis‐tern and there was no obvious compressive deformation at the bottom of the third ventricle ,there into the attachment sur‐face between the type I hamartoma and hypothalamic was small ,the attachment surface between the type II hamartoma and hypothalamic was wide ,but there was no obvious deformation at the bottom of the third ventricle (no deformation or de‐formation <10% ) .Type III (straddling type) defined as the hamartoma located partially within the hypothalamus and the third ventricle ,the affected deformation of the third ventricle bottom was obvious ;Type IV hamartoma was completely lo‐cated on the bottom of the third ventricle and located in the third ventricle .In this group ,1 case was in type Ⅰ ,1 case was in type Ⅱ ,4 cases were type III ,no one was in type IV .The patients who were in type II and type Ⅲ hypothalamic hamartoma were the patients with high wheezy epilepsy .After surgery and drug treatment ,epilepsy was significantly re‐duced .Hypothalamic hamartoma symptoms of TYPI patients were related to precocious puberty onset ,after surgical treatment ,the sex hormone level dropped to normal level of the childhood .Conclusion MRI has accurate classification of hypothalamic hamartoma and can provide basis for the choice of treatment and the establishment of surgical approach .