Application value of three dimensional arterial spin labeling method in preoperative glioma
ZHANG Yu-qin
XU Hai-dong
DONG Hai-bo
WANG Bo
LI Hui
HU Bin
WANG Ying-ying
LIANG Liang
Abstract：Objective To investigate the application value of three-dimensional arterial spin labeling in the preoperative glioma .Methods 45 patients with glioma proved by pathology (26 cases of high grade and 19 cases of low ) were setected and underwent the conventional MRI and 3D-ASL examination .We measured CBF value in the cerebral blood flow dia-gram ,one was on the most obvious perfusion area of the solid part of tumors and another on the contralateral area .Then TBFmax/CBF contralateral ratio was calculated .We also observed the whole brain perfusion .Results We found that 45 cases were gained high quality whole brain perfusion maps .High grade gliomas in cerebral blood flow map were shown dif-ferent degrees of highperfusion ,low grade gliomas were presented with perfusion of normal or reduced .TBFmax/contra-lateral ratios in the high and low grade gliomas were 3 .11 ± 1 .45 and 0 .86 ± 0 .28 ,with significant difference between the two groups ( P<0 .01) .9 cases of high grade gliomas appeared expansion vascular around the tumor ,and the CBF value was risen .Conclusion We thought 3D-ASL could gain glioma perfusion information to determine the grade before preop-eration and it was safe and noninvasive .And it could estimate the whole brain perfusion to help for formulating preopera-tive careful plan .
Keywords：Magnetic resonance imagingThree-dimensional arterial spin labelingGlioma
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1089-1092 )