Differential diagnosis of glioblastoma multiforme from metastatic brain tumor using proton magnetic resonance spectroscopy and diffusion-weighted image
YU Ke
LIU Qiang
HAO Li-wei
ZHANG Kai
GONG Tao
Abstract：Objective To evaluate the value of the diagnosis via 3 T MR 1 H-MRS and DWI between glioblastomas and solitary metastases .Methods 1 H-MRS and DWI were performed on 15 cases of glioma (grade Ⅳ ) and 15 cases of metas-tasis .ADC values were measured in solid portion ,peritumor zone and contralateral normal area .ADC values were meas-ured by using two kinds of ROI ,and whether the size of the tumor lesion ROI areas affect the measured parameter values was analyzed .The parameters of statistical difference between the two types of tumors were identified by using SPSS 13 .0 statistical analysis .Results There were statistically significant ( P < 0 .01) among NAA/Cr ,Cho/Cr ,NAA/Cho and ADC values in peritumoral edema between high-grade gliomas and metastases ,ADC values did not exist significant differ-ences ( P>0 .05) between the two tumor solid portion .The two different ROI methods applied in the intratumoral region of the tumor groups showed no statistical difference ( P>0 .05) .Conclusion 1 H-MRS and ADC values of peritumoral e-dema may be helpful in differential diagnosis between glioblastomas and solitary metastases .The size of two kinds of ROI has no significant effect on ADC values .
Keywords：Magnetic resonance spectroscopyDiffusion-weighted imagingGlioblastomaNeoplam metastasis
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1085-1088 )