Efficacy and safety of Allium covered metallic ureteral stent placement for maintenance treatment of ureteral stricture caused by idiopathic retroperitoneal fibrosis
ZHAO Guodong
HU Haopu
WANG Mingrui
BIAN Xiaolong
XIONG Jie
ZHANG Bao
XU Tao
HU Hao
Abstract：Objective To evaluate the safety and efficacy of Allium covered metallic ureteral stent placement as a maintenance therapeutic strategy for ureteral stricture secondary to idiopathic retroperitoneal fibrosis(iRPF)through a multicenter retrospective observational study.Methods A retrospective analysis was conducted on clinical data of patients diagnosed with iRPF-induced ureteral stricture,treated at Peking University People's Hospital,Aerospace Center Hospital,and Beijing Changping District Hospital of Integrated Traditional Chinese and Western Medicine between June 2020 and June 2024.All patients underwent Allium covered metallic ureteral stent implantation.Regular postoperative follow-ups were performed to assess technical success rates,stent patency rates,renal function(serum creatinine levels),improvement in the degree of hydronephrosis,and associated complications.Results In this study,a total of 45 stents were implanted in 27 patients(40 renal units),achieving a technical success rate of 100%.The median follow-up duration was 44 months.At the final follow-up,the median serum creatinine level decreased significantly from 121.8 μmol/L preoperatively to 100.0 μmol/L(P<0.001).The median renal pelvic width also exhibited a significant reduction from 1.7 cm preoperatively to 1.0 cm(P<0.001).During the follow-up period,the primary complication was stent migration(1 case,3.7%),which was successfully managed endoscopically.The primary patency rate was 97.5%,and the secondary patency rate following re-intervention was 100%.Conclusion The implantation of Allium covered metallic ureteral stents constitutes a safe and effective minimally invasive therapeutic modality for managing ureteral stricture caused by iRPF.It significantly improves renal function,relieves obstruction,and demonstrates favorable long-term patency outcomes.Stent migration represents the principal complication;however,its incidence is low and it can be successfully addressed through endoscopic intervention.
Keywords：Retroperitoneal fibrosisUreteral obstructionUreteral strictureAllium covered metallic ureteral stent
Publication Date：2025-12-25
Online Publishing Date：2026-01-16(First online date of this platform, not the publication date of the document)
Pages：6( 1491-1495,中插12-中插14 )