Determination of Ginsenoside Rg1 in Kuiyangling Capsule by HPLC
Pan Yanrong
Liu Yanxia
Chang Xiaoping
Abstract：Objective To detect the content of ginsenoside Rg1 in Kuiyangling capsule to control the quality of the product and enhance the binding force of the standard.Methods The content of ginsenoside Rg1 in Kuiyangling capsule was determined by HPLC.Chromatographic conditions were as follows:chromatographic column Hypersil BDS C18(250 mm×4.6 mm,5μm);mobile phase acetonitrile-0.05%phosphoric acid solution(21 :79),detection wave﹣length:203 nm,column temperature 30℃,flow rate 1.0 ml／min.The theoretical plate number calculated by ginsen﹣oside Rg1 could not be less than 5000.Results Ginsenoside Rg1 had a good linear relationship within the rage 0.852～4.260 μg(r＝0.9999).The average recovery rate of ginsenoside Rg1 was 97.86%,RSD＝1.65%.Conclusion HPLC method is stable,reliable,accurate and reproducible,which can be used for the quality control of Kuiyangling capsule.
Keywords：Kuiyangling capsuleGinsenoside Rg1HPLC method
Publication Date：2019-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 411-413 )