PrognosticEffectsofSerum AlbuminLevelinAdultswith Community－acquiredPneumonia
Ruan Guohu
Li Huan
Liu Weiqing
Abstract：Objective Toinvestigateprognosticeffectsofserumalbuminlevelsinadultswithcommunity－acquiredpneumonia(CAP)within24hofadmission.Methods 416CAPpatientsadmittedinthehospitalfrom2013to 2017wereobserved.Clinicalfeaturesandlaboratoryindexeswerecomparedamongdifferentserum albuminlevel groups.Serumalbuminlevelwasindependentvariable.Theprimaryendpointwas30－daymortality.Results The medianvalueofalbuminwas31g／L(IQR28～35).Aslevelsofserum albumindecrease,theriskofcomplications significantlyincreased(P＜0.001)withprolongedtimetoreachclinicalstability(P＜0.001)andprolongedhospital stay(P＜0.001);ICUadmissionrate,theneedformechanicalventilationand30－daymortalitywereallincreased (P＜0.001).Afteradjustingforpotentialconfoundersinamultivariatelogisticregressionanalysis,serumalbuminlevels(－5g／Ldecrease)wereindependentlyassociatedwithhigherriskof30－daymortality(OR2.11,95%CI1.73～2.56).Conclusion Serum albuminlevelwithin24hofadmissionisagoodprognosticmarkerinCAP.Physicians shouldconsideralbuminlevelwhenevaluatingtheseverityofillnessforpatientswithCAP.
Keywords：CommunityacquiredpneumoniaAdmissiontohospotial24hSerumalbuminPrognosis
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 598-601,604 )