Effects of Radiofrequency Ablation Combined with 125I Radioactive Particles Implantation on Immune Function and Therapeutic Efficacy of Hepatic Resection Patients
Zhang Yun
Abstract：Objective To investigate effects of radiofrequency ablation(RFA)combined with 125I radioactive particles implantation on immune function and therapeutic efficacy of hepatic resection patients.Methods 80 patients with liver cancer from Apr.2006 to Jul.2009 were randomly divided into control group and observation group with 40 patients in each group.Routine hepatic resection was used in control group.RAF combined with 125I radioactive particles implantation was used after routine hepatic resection in observation group.Immune function,serum tumor markers,short-term and long-term efficacy were observed in the two groups.Results CD4+ and CD3+ were significantly higher,CD8+ was lower in observation group than those in control group 7 d,14 d and 28 d after operation(P<0.05);Serum AFP levels were significantly lower in observation group than those in control group 7 d,14 d and 28 d after operation(P<0.05).The remission rate was significantly higher in observation group than that in control group(P<0.05).There was no significant difference in control rate between the two groups(P>0.05);The survival rates were significantly higher in observation group than those in control group 1,3 and 5 years after operation(P<0.05).Conclusion RFA combined with 125I radioactive particles implantation contribute to enhance immune function,reduce AFP expression and improve the prognosis of hepatic resection patients.
Keywords：Hepatic resectionRadiofrequency ablation125I radioactive particles implantationImmune functionTumor markers
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 134-136,139 )