Clinical Significance of Platelet Me,brane Glycoprotein Changes in Patients Co,bined with Coronary Artery Disease and Hypertension
Lin Daode
Ma Jianlin
Abstract:Objective To investigate the changes and significance of platelet membrane glycoprotein(GP)and platelet aggregation rate(PAgT)in patients combined with coronary artery disease( CAD)and hypertension( HP). Methods 116 patients with CAD were chosen as experiment group,including 36 patients with stable angina pectoris (SAP),38 patients with unstable angina pectoris(UAP),42 UAP patients with HP. 48 normal person were chosen as control group. Patients were divided into coronary artery events group(56 cases)and without coronary artery events group(60 cases)according to angina pectoris(AP)events. GP and PAgT were measured in each group. Results The levels of GP and PAgT were higher in UAP patients with HP than those in control group,patients with SAP as well as patients with UAP. The levels of GP and PAgT were higher in patients with UAP than those in control group and pa-tients with SAP. The levels of GP and PAgT were hither in coronary artery events group than those without coronary ar-tery events. Conclusion Increased level of GP and PAgT play an important role in occurrence of coronary artery e-vents in patients with CAD,which is more obvious in UAP patients with HP.
Keywords:Coronary artery diseaseHypertensionPlatelet membrane glycoprotein
Publication Date:2015-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:3( 246-248 )
