The Application of Stereotactic Biopsy for the Diagnosis of Intracranial Lesion in Patients with AIDS

Abstract：Objective To summarize our experiences of stereotactic biopsy for the diagnosis of intracranial le-sions in patients with AIDS. To explore operation methods and technical points,decrease complications and increase positive diagnostic rate. Methods 6 AIDS patients(3 males and 3 females)with multiple intracranial lesions under-went stereotactic biopsy were analyzed retrospectively. The patients were 15 to 49 years(mean 37. 3 years)old and dis-ease history ranged from 10 days to 1 year. Patients underwent MRI guided stereotactic brain biopsy. Pathological ex-amination was taken after operation and immunohistochemical examination was taken if necessary. Results Opera-tions for 6 patients were successful. Pathology results showed:inflammation in 3 cases,astrocytoma in 1 case,toxoplas-mic encephalitis in 1 case,glial cells hyperplasia in 1 case. Patients were followed up from 8 months to 4 years. 1 case fully recovered,4 cases with significant improvement in symptoms and 1 died. Conclusion Stereotactic biopsy is a safe and effective way for the diagnosis of intracranial lesions in AIDS,which is helpful for making treatment plan and improve prognosis.