Clinical Observation of Dexmedetomidine in Laryngeal Mask Airway under General Anesthesia in Bronchial Intervention Surgery

Abstract：Objective Toobservetheeffectofdexmedetomidineinlaryngealmaskalrwayundergeneralanesthe-sialnbronchialinterventionsurgery.Methods 52patientsunderwentlaryngealmaskalrwayundergeneralanesthesia in bronchial intervention surgery were randomly divided into dexmedetomidine group and control group with 26 patients in each group. 1. 0μg/kg dexmedetomidine was given intravenously with micro-pump 10 min before anesthesia in-duction. Drug administration rate was 0. 4~0. 6 μg/kg/h after induction until the end of surgery. Normal saline was given instead of dexmedetomidine in the control group. Heart rate( HR),arterial blood pressure,alrway pressure, ETCO2 and oxygen saturation( SpO2 )were recorded at the time of entering operation room( T0 ),before laryngeal mask alrway(T1),1 min after laryngeal mask alrway(T2),15 min in surgery(T3),stopping all drugs at the end of surgery( T4 ),and awakening when pulling out laryngeal mask( T5 ). Ramsay sedation score,body movement and coughreflexwererecordedbeforeandafterremovinglaryngealmask.Results HRandarterialbloodpressurede-creased after anesthesia induction and before insertion of laryngeal mask in both groups. HR and arterial blood pres-sure increased in T2,T3,T4 and T5 in the control group(P<0. 05). There was no significant difference between HR and arterial blood pressure in dexmedetomidine group(P>0. 05). Ramsay score in dexmedetomidine group was superior to that in the control group;Body movement and cough reflex were less in dexmedetomidine group( P<0. 05).Conclusion Dexmedetomidineinlaryngealmaskalrwayundergeneralanesthesialnbronchialinterventionsur-gery can provide a more stable anesthetic effect,malntaln stable hemodynamics and reduce adverse reactions without affecting breath and analepsia.