Relationship among Ultrasound Plaque Stability,Intima - medial Thickness,Serum C - reaction Protein and Cerebral Infarction

Ai Qingxiu; Cheng Xinyao

Abstract：Objective To investigate the relationship among carotid plaque stability,intima - medial thickness (IMT),serum C - reaction protein(CRP)and cerebral infarction. Methods 112 hospitalized patients with cerebral infarction were taken as group I,while 93 healthy cases as group II. Carotid plaque stability,IMT and CRP were meas-ured and evaluated. Results ①Incidence of plaque was 76. 8% with IMT(1. 24 ± 0. 31)mm and serum CRP(2. 14 ± 0. 85)mg/ L in group I. Incidence of plaque,IMT and CRP were 16. 1% ,(0. 59 ± 0. 06)mm and(2. 14 ± 0. 85) mg/ L respectively in group II. There were significant differences between the two groups(P ﹤ 0. 05). ②There were 19 patients with stable plaque(22. 1% )in 86 patients in group I. The incidence of unstable plaque was significantly high-er than stable plaque in patients with cerebral infarction(P ﹤ 0. 05). ③IMT was(0. 87 ± 0. 11)mm with CRP(4. 45 ± 1. 82)mg/ L in for patients with stable plaque. IMT was(1. 21 ± 0. 29)mm with CRP(8. 03 ± 2. 77)mg/ L in patients with unstable plaque(P ﹤ 0. 05). ④CRP was positively correlated with IMT in group I(r = 0. 73,P ﹤ 0. 05). CRP was positively correlated with IMT in group II(r = 0. 67,P ﹤ 0. 05). The total CRP was positively correlated with total IMT (r = 0. 69,P ﹤ 0. 05). Conclusion ①The incidence of carotid plaque is higher in patients with cerebral infarction.②The incidence of unstable plaque is significantly higher than stable plaque in patients with cerebral infarction. ③IMT and CRP are higher in patients with unstable plaque. There are relationships among carotid plaque stability,IMT, CRP and cerebral infarction,which may have predictive significance for cerebral infarction.