A Study on Relationship of PCNA Expression and DNA Ploidy Detection with the Metastasis of Cervical Squamous Cell Carcinoma
Abstract:To explore the correlation between the tumor prolifer ative activity and the metastasis of cervical squamous cell carcinoma, the expre ssion of Proliferating Cell Nuclear Antigen(PCNA) and DNA Content Index (DI) wer e investigated using SP immunohistochemical staining and image analysis in 65 ca ses. Result:The expression of PCNA and DNA content were correlated with tumor differentiation and metastasis; as well as there was a striking association betw een PCNA and DI.These indicated that higer proliferative activity always means l ower differentiation and higer metastasive potention of the cervical squamous ce ll carcinoma.
Keywords:Cervical squamous cell carcinomaMetastasisPCNADI
Publication Date:2001-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:2( 80-81 )
