Comparison of the periodontal status of the first and second molars in the presence of non-impacted third molars
GAO Rui
ZHANG Lin-lin
GAO Li-na
CHEN Xing-yu
CHEN Fang
YANG Yang
LIU Hua-jie
CHEN Fa-ming
WU Rui-xin
Abstract：AIM:To compare the periodontal status and subgingival plaque microecology of the first and second molars when non-impacted third molars were present,through periodontal clinical examination and 16S rRNA high-throughput sequencing technology.METHODS:Subjects were included according to the inclusion and exclusion criteria.Oral hygiene instruction and supragingival plaque removal were performed.Subsequently,periodontal probing examination was conducted on the first and second molars of the observed regions,and the local subgingival plaque was collected.Full-Length 16S rRNA Sequencing was carried out using the PacBio platform.Finally,compared the periodontal clinical indicators and local microbial community characteristics of the first and second molars.RESULTS:The average probing depth,percentage of bleeding on probing,percentage of deep periodontal pockets,and plaque index of the second molars adjacent to non-impacted third molars were significantly higher than those of the first molars.The diversity and richness of subgingival plaque microorganisms of the second molars were significantly greater than those of the first molars.β-diversity analysis showed significant differences in the microbial community structure between the two groups.In the subgingival plaque of the second molars,the relative abundances of periodontal pathogens such as Porphyromonas gingivalis and Fusobacterium nucleatum were significantly higher than those of the first molars.CONCLUSION:When adjacent to non-impacted third molars,the periodontal status and subgingival plaque microecology of the second molars are worse than that of the first molars.
Keywords：periodontitisfull-length 16S rRNA sequencingfirst molarssecond molarsnon-impacted third molars
Publication Date：2025-05-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：8( 254-261 )