Research progress in the relationship between chronic periodontitis and Alzheimer’s disease
GU Xing-hua
MA Ming-yang
YU Feng
Abstract：Chronic periodontitis(CP)is an oral chronic infection/inflammatory condition,identified as a source of mediators of inflammation into the blood circulation,which may contribute to exacerbation of several diseases. Alzheimer's disease (AD)is a neurodegenerative disease characterized by progressive cognitive decline and memory loss,inevitably leading to complete loss of mental faculties and death. There is increasing evidence that inflammation plays a key role in the pathophysiology of AD.The relationship between CP and AD has been confirmed. In this paper, the research progress on the association between CP and AD is overviewed.
Keywords：chronic periodontitisalzheimer's diseasesystemic inflammationcytokines
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 364-368 )