The research progress in utilizing oriented amorphous calcium phosphate nano-particles for the remineralization of dental hard tissues
SHEN Min-juan
Abstract：Amorphous calcium phosphate plays a basic role in the mineralization of dental hard tissues and bones. As we all know,the living bodies are able to regulate amorphous calcium phosphate by secreting corresponding proteins. Amorphous calcium phosphate,eventually,can be transformed into hydroxyapatite crystals with excellent me-chanical properties. Using biomimetic analogues to control the oriented transformation of amorphous calcium phosphate can achieve biomimetic mineralization mimicking the similar structure of dental hard tissues in vivo. Meanwhile,biomi-metic mineralization experiments may verify the real mechanisms in the in vivo mineralization. This review summarizes the mechanisms of oriented arrangement about amorphous calcium phosphate both in vivo and in vitro,provides signifi-cant information about the biomimetic remineralization of dental hard tissues and bones with amorphous calcium phos-phate as an initial material.
Keywords：amorphous calcium phosphatebiomimetic mineralizationdental hard tissues
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 240-245 )