Changes of Porphyromonas gingivalis and its virulence factor FimA genotype in the adolescent patients underwent orthodontic treatment
SUN Yu-gang
CHEN Yan-hua
WANG Lin
GUO Yang
ZHANG Qiang
Abstract：AIM:To explore the changes of Porphyromonas gingivalis (Pg) and its virulence factor FimA in the adolescent patients underwent ortIhodontic treatment.METHODS:61 orthodontic teenagers with healthy gingiva underwent orthodontic treatment.Givgival crevicular-fluid(GCF) of the subjects was collected before and 1,2,3 and 6 month after treatment respectively,simultaneously the gingival index (GI) of one-to-one correspondence was examined,Pg and its virulence factor FimA in GCF of each sample were detected by 16SrDNA PCR technique.SPSS 20.0 software package was used to analyze the data.RESULTS:3 months after treatment.Pg and FimA Genotype Ⅱ,Ⅳ and Ⅴ in GCF were increased (P ＜ 0.05).The positive growth of Pg and the 6 genotypes in the first 3 monthsafter treatment were increased,and the highest level appeared at the third month,then gradually decreased and returned to the prior treatment state in the sixth month.Significant positive correlation was observed between Pg and GI and FimA genotype Ⅰ,Ⅰb,Ⅱ,Ⅳ and Ⅴ respectively (P ＜ 0.05).CONCLUSION:During the orthodontic treatment in adolescents,the increase of Pg and FimA can be caused by the wearing the appliance in the early stage,that may induce gingival inflammation.
Keywords：orthodontic treatmentadolescensPorphyromonas gingivalisFimAPCR
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 684-688 )