In vitro evaluation of the bacteriostatic effects of chlorhexidine gel and calcium hydroxide
LI Shao-rong
LIU Ying
YANG Zi
HOU Ben-xiang
Abstract：AIM:To evaluate the antibacterial activity of chlorhexidine (CHX) gel and/or calcium hydroxide (CH) paste against endodontic pathogens.METHODS:Agar diffusion test and direct contact test were used to obtain the inhibition zone and the minimum inhibition concentration (MIC) of CHX,CH and CHX + CH against 4 endodontic pathogens.Data were statistically analyzed using Kruskal-Wallis test.RESULTS:The diameter of the inhibition zone of the preparations was as following:CHX ＞ CHX + CH ＞ CH(P ＜0.05).CHX + CH showed the strongest inhibition effect for all the pathogens.In the inhibition of enterococcus faecalis the effeciency of the preparations was CHX + CH ＞ CHX ＞ CH(P ＜ 0.05);in the inhibition of Porphyromonas gingivalis,Actinobacillus actinomycetem comitans and Parvimonasmicra CHX ＞ CH ＞ CHX(P ＜ 0.05).CONCLUSION:The diffusion ability of CHX gel was the largest while the direct antibacterial activity of CHX + CH was the strongest against the 4 endodontic pathogens.
Keywords：chlorhexidine gel (CHX)calcium hydroxide paste (CH)enterococcus faecalisparvimonasmicrabacteriostasis
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 644-648 )