The effect of periodontal basic treatment on the levels of serum leptin and glycated hemoglobin A1c in patients with type Ⅱ diabetes and chronic periodontitis
ZHOU Yun
CUI Yan-jun
Abstract：AIM:To explore the effects of periodontal basic treatment on periodontal clinical parameters,glycated hemoglobin A1c(GHbA1c) and serum leptin in patients with type Ⅱ diabetes and chronic periodontitis(DMCP).METHODS:40 patients with type DMCP and 40 patients with chronic periodontitis (CP) underwent periodontal basic treatment.The bleeding index(BI),bleeding on probing(BOP),periodontal probing depth(PD),clinical attachment loss(CAL),plaque index(PLI),glycated hemoglobin A1c(GHbA1c) and serum leptin concentration were examined at baseline,1 and 3 months after treatment.RESULTS:There was no significant difference in BI,PD,PLI and BOP between the 2 groups at baseline (P ＜0.05).At the 1st and 3rd month after treatment,PD,BI,PLI and BOP in the 2 groups were significantly decreased (P ＜ 0.05),in DMCP group decreased more than in CP group (P ＜ 0.05),CP group did not show significant change of CAL level (P ＞ 0.05).The levels of GHbA1c and leptin were significantly decreased after treatment (P ＜0.05).GHbAlc and leptin of group DMCP was significantly higher than those of CP group in the whole treatment period.CONCLUSION:Periodontal basic treatment can significantly improve periodontal clinical parameters and regulate glucose metabolism in diabetic patients with chronic periodontitis.
Keywords：periodontal basic treatmenttype Ⅱ diabeteschronic periodontitisglycated hemoglobin A1cleptin
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 583-587 )