Clinical observation of platelet rich fibrin in periodontal bone graft surgery
LEI Chao-feng
WANG Ying-bo
XU Yi
Abstract：AIM:To observe the effects of second-generation platelet concentrated platelet-rich fibrin (PRF) on the periodontal tissue healing.METHODS:20 patients with intra-bony defects of chronic periodontitis were randomly divided into the test and the control groups (n =10).The patients in test group were treated with PRF and Bio-Oss combination,those in the control were treated with Bio-Oss alone.Probing depth (PD),attachment level (AL),Mazza bleeding index (BI) and radiographic measurements of intra-bony defect(IBD) were recorded at pre-surgical baseline and 6 months post-operatively.RESULTS:All the clinical and radiographic parameters of the 2 groups were improved after treatment(P ＜0.05).Mean PD reduction and AL gain in test group were more than in the control group(P ＜ 0.05).No statistically significant difference was found in BI and IBD between 2 groups.CONCLUSION:PRF combined with Bio-Oss bone graft may accelerate periodontal soft and hard tissue healing.
Keywords：platelet-rich fibrinchronic periodontitisbone graft surgery
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 525-528 )