The effect of semiconductor laser on pulp tissue and substance P expression during whitening procedure
LI Chun-nian
WU Ming-xuan
Abstract：AIM:To observe the expression of Substance P (SP) in dental pulp tissue after semiconductor laser treatment for whitening.METHODS:100 male SD rats aged 3 months were randomly divided into a normal control group(n=10, group A), continuous-wave semiconductor laser group (group B, n=40),and pulse generation laser group (group C, n=40).In group A, all rats were directly sacrificed.In group B and C, maxillary first and second molars of all rats were respectively irradiated by continuous and pulsing semiconductor laser at a frequency of 7 W, 20 Hz, 15 s.The rats were killed immediately after treatment, at day 1, day 3 and day 7 after treatment respectively(n=10).Histological sections of maxillary first and second molars were stained with HE and IHC respectively.RESULTS:Group B and C presented higher degree of hyperemia in pulp than that in group A, group B showed even higher degree of hyperemia than group C.The expression of SP in pulp tissue in group B and C was higher than that in group A(P<0.05).The level of SP started to rise immediately after irratiation and reached the highest level at day 3, and then decreased.At the same time, the SP level in group B was higher than that in group C(P<0.05).CONCLUSION:Continuous-wave laser is stronger than pulse laser in the stimulation of pulp tissues.Laser irradiation can cause increased pain transmitter SP expression in the pulp tissue within 3 days after irradiation.
Keywords：semiconductor laserwhitening procedurepulp tissuesubstance P(SP)
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 391-395 )