The effect of smoking on HGF expression of in gingival sulcus fluid in the patients with chornic periodontitis before and after the periodontal basic treatment
LIU Feng
ZHANG Hang-tao
XIAO Yue
HU Li-man
WANG Jing
SU Sha
LIU Chong
YIN Yao-tian
HU Wei
LIU Han-zhong
Abstract：AIM: To study the influence of smoking on HGF expression in gingival sulcus fluid(GCF) in the patients with chronic periodontitis befeor and after basic treatment.METHODS: 60 patients with chronic periodontitis, 30 smoking(group S) and 30 non-smoking(group NS), were included.Before and 4 weeks after basic treatment, tooth plaque index (PLI), exploration probing depth (PD), gingival sulcus bleeding index (SBI) and attachment loss (AL) were examined.HGF level in GCF were measured by ELISA.RESULTS: Befeor treatment PLI and HGF level in group S were higher than those in group NS(P<0.05).After treatment, PLI, SBI, PD and AL in both groups were decreased, in group NS were lower than those in group S(P<0.05).The HGF concentration in both groups were reduced after treatment(P<0.05), in group NS was lower than in group S.CONCLUSION: HGF level is related with smoking in patients with chonronic peridontitis.
Keywords：smokingchronic periodontitisgingival crevicular fluidhepatocyte growth factor
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 334-337 )