Correlation between smoking and IL-17A expression in peri-implant sulcus fluid of patients with peri-implantitis
JIANG Han
LI Jing
LIU Li-jun
LIU Hui
Abstract：AIM: To explore the effects of smoking on IL-17A expression in peri-implant sulcus fluid(PISF) of patients with peri-implantitis.METHODS: The patients were divided into smoking group(n=13) and non-smoking group(n=13).Implant site group of the subjects was included into implant group and the contralateral natural teeth group was included into control group.Modified gingival index(mGI),modified sulcus bleeding index(mSBI),probing depth(PD),alveolar bone loss(aBL)were detected,and the gingival sulcus fluid was collected.The concentration of IL-17A was measured by ELISA.RESULTS: In smoking group,the IL-17A concentration in implant group was higher than that in the control group (P<0.05).Both implant sites and contralateral natural teeth had significantly higher expression of IL-17A in smoking group than that in nonsmoking group (P<0.05).In both smoking and nonsmoking groups,IL-17A concentration was positively correlated with PISF volume.Furthermore,IL-17A concentration in smoking group was positively correlated with AL and PD,and negatively correlated with mGI and mSBI.CONCLUSION: Smoking can lead to increased expression of IL-17A,IL-17A can be used as one of inflammatory markers in peri-implantitis.It is speculated that smoking is one of the risk factors of peri-implantitis.
Keywords：smokingperi-implantitisinterleukin(IL)-17A
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 266-270 )