Detection of Porphyromonas gingivalis rag genotypes in adolescence gingivitis patients
YU Miao
LI Ti
ZHANG Yu-jie
LI Zhi
Abstract：AIM:To investigate the distribution of Porphyromonas gingivalis(Pg)rag genotypes in adoles-cence gingivitis patients.METHODS:64 adolescent gingivitis patients (GI≥1,PD≥3 mm)and 56 gingivally healthy controls (GI=0,PD<3 mm)were included.Gingival crevicular fluid(GCF)was collected from all subjects. Pg and rag genotypes of Pg in GCF were detected by PCR method.RESULTS:The detection rate of Pg in GCF of the patients and healthy controls was 65.63%(42/64)and 33.93%(19/56)respectively(P<0.05).In Pg postive pa-tients(n=37 ),the rag genotypes in Pg positive samples was in the following order:rag -3 (16/37 ),rag -1 (9/37),rag-4 (7/37)and rrag-2 (5/37),in the controls(n=10)was rag-3(5/10),rag-2(2/10),rag-4 (2/10)and rag-1(1/10)(P<0.05).CONCLUSION:Various rag genotypes can be found in GCF of adolescent gingivitis patients.Rag-1 and rag-3 might have more close correlation with the development of adolescent gingivitis.
Keywords：porphyromonas gingivalis(Pg)genotyperag gene
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 659-661 )