Changes of IL-35 levels in gingival crevicular fluid before and after basic periodontal treatment in periodontitis patients
MA Ting-ting
WANG Li
JIA Shu-fang
DUAN Li-rong
Abstract：AIM:To study the correlation between IL-35 levels in gingival crevicular fluid (GCF)and clinical index in patlents with periodontitis.METHODS:30 periodontitis patients were divided into mild,moderate and severe chronic periodontitis groups (n=1 0 )based on clinical index.GCF was collected at the same site before and 1 month after periodontal treatment.Bleeding index (BI),probing depth (PD)and clinical attachment loss (CAL)were measured and recorded.ELISA was used to determine the concentration IL-35 in GCF.RESULTS:1 month after treatment,IL-35 levels and clinical indices were significantly lower than those before treatment in all the 3 groups(P<0.05 ).Furthermore,the decreasing effect was more significant in moderate and severe groups than in mild group (P<0.05).Correlation analysis showed no significant correlation between the change of IL-35 levels and the change of clinical indices(P>0.05).CONCLUSION:IL-35 might be involved in the process of periodontitis.
Keywords：periodontitisperiodontal basic treatmentinterleukin-35 (IL -35 )gingival crevicular fluid(GCF)
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 617-619 )