The effect of orthodontic torsional force on TNF-αexpression in adult dental pulps
GUO Xin-xing
CHEN Jing
ZHANG Yong
Abstract：AIM:To investigate the effects of orthodontic torsional force on TNF-αexpression in adult dent-al pulps. METHODS:112 maxillary first premolars in 56 adult orthodontic patients were randomly divided into exper-imental group (n=96) and control group (n=16). The teeth in experimental group were added with 4, 6, and 8 ounces orthodontic torsional force for 1, 2, 3 and 4 w respectively(n=8). At the end of the treatment, the teeth were extracted and dental pulp tissues were removed. TNF-α expression in the dental pulps were detected by ELISA. RESULTS:In 4 and 6 ounce torsional force treatment groups TNF-α expression did not show any change up to 3 w, but increased at the end of 4 w in the 2 groups(P<0. 05). However, TNF-αexpression significantly increased at the end of 2 w in the 8 ounce torsional force treatment group(P<0. 05), and decreased to control level at the end of 3 and 4 w. CONCLUSION:Torsional force may change TNF-α expression in adult dental pulp.
Keywords：torsional forcedental pulpTNF-αorthodontic treatment
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 615-617,623 )