Establishement of experimental periodontitis model in goats
LI Jun
QIAO Wen-jing
LIU Qi
Abstract：AIM: To establish experimental periodontitis model in goats. METHODS:The mandible first premolar and first molar at one side of 10 goats were ligated with orthodontic ligature and the periodontal tissues were destructed mechanically, while the mandibular first premolars and first molars on the other side were served as the con-trols. At 4 and 10 w after ligation, the teeth were scanned with CT. At 10 w after ligation, the animals were sacrificed and the periodontal tissues were subjected to histological observation. RESULTS:Histological results and CT imaging analysis showed that animals in experimental group had different degrees of periodontal tissue loss at 4 and 10 w after ligation. Moreover, at 10 w, intermediate periodontitis was observed in the goats. CONCLUSION:Goat experimental periodontitis model can be established by orthodontic ligature method.
Keywords：periodontitisanimal modelsCT three-dimensional imaginggoat
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 427-429 )