Estrogen receptor and aromatase expression in gingival carcinoma tissue
WANG Qiu-rui
YANG Jian
ZHAO Hua-ping
ZHANG Ying-huai
Abstract：AIM:To investigate the expression of estrogen receptor (ER)and aromatase in gingival carcino-ma.METHODS:ER and aromatase were detected by immunohistochemical staining SP method in gingival carcinoma (n=28)and normal gingival tissues(n=15).RESULTS:Positive expression rates of ER and aromatase expression in gingival carcinoma were 50.00% and 42.86% ,in normal gingival tissues were 13.33% and 6.67%,respectively (P<0.05).No significant correlation was found between ER and aromatase in gingival carcinoma.CONCLUSION:Estrogen metablism might be related to gingival carcinoma.Aromatase is not the exclusive reason of the high positive rate of ER.
Keywords：gingivasquamous cell carcinomaestrogen receptor (ER)aromataseimmunohistochemistry
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 304-307 )