The effects of one-visit occlusal rehabilitation on the expression of injury-sensitive proteins in rat′s masseter muscle
CUI Jie
YU Shi-bin
HE Hui-ming
ZHANG Chun-bao
Abstract：AIM:To investigate the effects of one-visit occlusal rehabilitation(OR)on the expression of desmin and skeletal troponin I (sTnI)in rat's masseter muscle.METHODS:60 healthy 8-week-old male SD rats were randomly divided into control group (C),sham operation group (S)and one-visit OR group (T)(n=20).In T group,the crown height of the upper molars of the rats were shortened by 1 .2 mm mechanically and gradually,6 weeks later,the occlusal splints were made and adhered to the molar surface by resin bonding.In S group the sham operation was used,the controls were without any operation.5 rats in every group were sacrificed at 3 d,7 d,14 d,and 28 d af-ter operation respectively.The deep masseter muscles were excised,western blot method was used to detect the expres-sion of desmin and sTnI.RESULTS:① The expression of desmin and sTnI showed no significant difference between group C and S(P>0.05).②Desmin and sTnI in the masseter muscle in group T decreased 3 d after OR(P<0.05), decreased to the lowest level 7 d after OR(P<0.05 ),then began to increase gradually and reached the normal level 28 d after the OR(P>0.05).CONCLUSION:One-visit occlusal rehabilitation can cause the degradation of desmin and sTnI in masseter muscle.However,the damage is reversible.
Keywords：one-visit occlusal rehabilitationmasseter muscledesminskeletal troponin I
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 20-23,27 )