Antimicrobial effect of different root canal irrigant combinations on infected root canals under passive ultrasonic irrigation
ZHANG Min
QIU Jun
HOU Hui
LI Lin
ZHOU Jie
FAN Xiao-min
Abstract：AIM:To compare the antimicrobial effect of different root canal irrigant combinations under pas-sive ultrasonic irrigation in root canals.METHODS:90 human root canals contaminated with Enterococcus faecalis were randomly divided into 4 experimental groups (group A:25 g/L NaClO/20 g/L CHX,group B:25 g/L NaClO 30 mL/L H2 O2 ,group C:10 g/L NaClO 20 g/L CHX,group D:10 g/L NaClO/30 mL/L H2 O2 )and 2 two control groups (group E:52.5 g/L NaClO,group F:0.9%normal saline,n=10,5 were used as base line control).Before and after treatment bacterial content on the surface of root canal walls and at 100,200,300 μm in depth inside the dentinal tubules was measured and analyzed by means of one-way analysis of variance.RESULTS:On the surface and at different depths of dentine,the bactericidal efficiency of groups of A,B,C,D and E were significantly greater than that of group F (P<0.05).At all depths,the bacterial reduction of group A was more than that of group B,C and D (P<0.05 ),similar to that of group E (P>0.05 )except at depth of 200 ~300um,the bactericidal efficiency of group A was lower than that of group E (P<0.05 ).Moreover,the bactericidal efficiency of group C was lower than that of group A (P<0.05),but higher higher than 90%and than that of group B and D(P<0.05).The bactericidal efficiency of group B and D was similar (P>0.05).CONCLUSION:The combination of 25 g/L NaClO and 20 g/L CHX can be considered to be the ideal irrigant of root canal disinfection.
Keywords：root canal irrigantspassive ultrasonic irrigation (PUI)sodium hypochlorite (NaClO)chlorhexi-dine digluconate (CHX)combinationbactericidal effect
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 649-653 )