The effect of gallnut water extracts on collagenⅠ synthesis in human dental pulp cells
LU Jin
XU Xing-xing
LI Xin
JIA Zhen
TANG Rong-yin
WANG Jin
Abstract：AIM:To observe the effects of gallnut water extracts on collagen I synthesis of human dental pulp cells.METHODS:Cultured human dental pulp cells of passage 6 were treated with 5 μg/mL and 10 μg/mL of gallnut water extracts for 3 d respectively.Collagen I expression of the cells was detected by immunocytochemistry method.The quantitative data was obtained by HPIAS-1000 image analysis system.RESULTS:Collagen I protein was expressed in of both gallnut water extract treated dental pulp cells and control cells,and located mainly in cyto-plasm.Gallnut water extracts treatment dose-dependently increased collagen I protein expression (P<0.05).CON-CLUSION:Both 5 μg/mL and 10 μg/mL gallnut water extracts can enhance collagen I protein expression in human dental pulp cells,indicating that it is potential to promote dental pulp cells to differentiate into odontoblasts.
Keywords：gallnut water extractsin vitro culturehuman dental pulp cellscollagen I
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 642-644 )