The effects of bone morphogenetic protein 2 on the proliferation, differentiation and migration of periodontal ligament stem cells
HUANG Zi-xian
LIANG Min
Abstract：Bone morphogenetic protein-2 (BMP-2) is a growth factor which has regulating effects on cellu-lar morphogenesis, proliferation and differentiation.Periodontal ligament stem cells (PDLSCs), as the promising seeds in periodontal regeneration , are capable of self-renewal with multi-differentiation potency .The effects of BMP-2 on PDLSCs remain unknown .It is of great importance to study the biological effects of BMP-2 on PDLSCs.This review fo-cuses on the influence of BMP-2 on PDLSCs in terms of proliferation , apoptosis , differentiation and migration .
Keywords：BMP-2periodontal ligament stem cellscell proliferationcell differentiationcell migration
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 549-553 )