The effect of geniposide on the physiochemical properties of demineralized dentin
SHA Xin-jia
WANG Yu-rui
ZHOU San-ling
LI Na
LIU Rui-rui
Abstract：AIM:To explore the roles of natural cross-linking agents-geniposide on the physiochemical properties of demineralized dentin.METHODS:Fresh dentin specimens from extracted human third molars were pre-pared and powdered in liquid nitrogen.After demineralized for 5 hours in 100 g/mL phosphoric acid,the samples were preconditioned by geniposide-based preconditioners at 0.05 mg/mL,0.1 mg/mL and 0.15 mg/mL solved in distilled water,ethanol and acetone respectively.The tensile strength of the specimens was examined using omnipatent material machine and the cross-linking degree of the dentin powders were evaluated by triketohydrindene hydrate stain method. RESULTS:Geniposide-based preconditioners increased the cross-linking degrees of dentin collagens concentration-dependently(P<0.05).Demineralized dentin pretreated by organic geniposide solution showed higher cross-linking a-bility than by inorganic solutions at the same concentration (ethanol group >acetone group >distilled water group, P<0.05).Geniposide-based preconditioners with three solvents promoted the ultimate tensile strength of demineral-ized dentin concentration-dependently (P<0.05 ),there was no significant difference among 3 solvent groups (P>0.05).CONCLUSION:Geniposide can concentration-dependently promote the cross-linking ability and ulti-mate tensile strength of the demineralized dentin,the effects of geniposide with ethanol solvent is the strongest.
Keywords：geniposidedentincross-linking degreeultimate tensile strength
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 451-454 )