Ornidazole and carboxymethyl chitosan gel as an adjunct in the treatment of periodontal diseases
TANG Tao
LI Ruo-xuan
LI Min
XIE Tong
ZHANG Mei-feng
Abstract：AIM:To examine the effect of ornidazole and carboxymethyl chitosan gel(OCCG)as an adjunct in the treatment of periodontal diseases.METHODS:A randomized,single blind and controlled clinical trial was per-formed.59 periodontitis patiens were randomly divided into periodontal therapy only group (control,n=31)and perio-dontal therapy plus OCCG group (n=28).Plaque index (PLI),bleeding index (BI),probing depth (PD),attache-ment loss (AL),the number of spirochete(s)and trypsin-like proteinase in subgingival plaque were measured and recorded at baseline,7,14,21 d and 28 d after treatment.RESULTS:Similar parameters were found between the 2 groups at baseline(P>0.05).After treatment,both groups showed significant decrease in clinical parameters except PD and AL at all time points (P<0.05).The experiment group showed better effects in the decrease of PLI,BI,S%and OD value than control group (P<0.05).The effective rate of experiment and control group5 were 89.3% and 75.8% respectively (P<0.05).COCLUSION:Ornidazole and carboxymethyl chitosan gel as an adjunct are favora-ble in the treatment of periodontal diseases.
Keywords：ornidazole of carboxymethyl chitosan gelperiodontal pocketBANA
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 419-422,410 )