The function of AP-1 in the develotment of dentine and enamel
YI Si-jian
LIU Jian-guo
WU Jia-yuan
Abstract：AP-1isatranscriptionfactor,adimercomplexofc-Junandc-Fosencodedbyproto-onco-gene.As a transcription regulatory factor,it binds to DNA.Through activating or inhibiting target gene transcription,it is involved in many cell activities,such as cell proliferation,apoptosis,cell survival and tumor development .AP-1 was recently found to be expressed in the process of tooth development,mainly in mature ameloblasts and odontoblasts. This review summarizes the regulatory role of AP-1 in dentine and enamel development.
Keywords：AP-1c-Fosc-Junodontoblastameloblast
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 363-366,322 )