Ultrastructural localization of TGF-βs exposure in dentine by cavity conditioning agents
Abstract：AIM: To investigate the ability of cavity conditioning agents toexpose TGF-βs from mature human dentine at sites of cavity preparation. METHODS: Gold-labelled Immunohistochemical staining and SEM. RESULTS: 170g/L EDTA exposed large amounts of TGF-β1 from dentine and clearly removed any Smear layer present; 30g/L sodium hypochlorite and 100g/L citric acid caused some exposure of TGF-β1 and partial removal of the smear layer, while in PBS treated samples only minimal TGF-β1 was exposed. TGF-β2 and TGF-β3 were not detected in all groups. CONCLUSION: TGF-β1 is the most prevalent TGF-β isoform in dentine and EDTA is the most effective cavity-conditioning agent in exposing this growth factor from dentine.
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Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 20-23 )