The experimental study on relationship between time for placement of a barrier membrane and periodontal regeneration in dogs
Abstract：AIM: The optimal time for placement of a barrier membrane beestablished in guided tissue regeneration needed to achieve maximum periodontal regeneration. METHODS: Periodontal defects were created on buccal side of mesial root of mandibular third and fourth premolars in dogs. An expanded polytetrafluoroethylene(ePTFE) membrane was used to left in place for 2, 3, 4 and 8 weeks respectively. In the control defects(right mandibular second premolar), no membrane was used. All animals were sacrificed at the end of 8 weeks. Study and histologic analysis were performed. RESULTS: The group in which the membranes were left in place for 3 weeks showed more new bone and new cementum and less junctional epithelium than the controls. However, no significant difference of periodontal regeneration was found among the 3-week, 4-week and 8-week groups. CONCLUSION: The shortest time for placement of a barrier membrane needed to achieve maximum periodontal regeneration is 3 weeks.
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Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 17-19 )