The experimental study of effect of calcium channel blocker nifedipine on the proliferation of gingival fibroblasts in vitro
Abstract：AIM: To investigate the effects of nifedipine, a calcium channelblocker, on cellular proliferation of gingival fibroblasts in vitro. METHODS: Gingival fibroblasts were cultured and incubated with various concentrations of nifedipine(1?200, 360,108 and 23.5μg/L)for 7days. RESULTS: Cell numbers were different significantly among those groups on the sixth and seventh day, especially between 1?200μg/L(or 360μg/L) group and other groups. CONCLUSIONS: Nifedipine can influence the proliferation of gingival fibroblsts at high concentration.
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Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 7-9 )