The effect of insulin - like factor - [[ on the biological activities of cultured human
FENG Xue
LIN Zhu
DUAN Yin-zhong
Abstract：AIM: To investigate the effect of Insulin- like factor- Ⅱ(IGF- Ⅱ)on the biological activities of cultured human periodontal ligament fibroblasts(PDLF). METHODS: Seeding certain concentration of the fifth generation of cultured PDLF into 96 plates, to determine proliferation and the activity of alkaline phosphatase(ALP) using MTT method and ALP kit respectively after the input of IGF - Ⅱ . RESULT: IGF- Ⅱ could enhance both of proliferation and ALP activitywithin the experimental concentration. CONCLUSION: IGF- Ⅱ could influence the biological activities of PDLF, and itmight modulate the remodeling process of peridontal tissue through the function of PDLF
Keywords：insulin - like faotor - Ⅱperiodontal liyament fibroblost(PDLF)alkaline phosphatasea(AlP)
Publication Date：2000-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 265-267 )