Research progress on the regulation of Fas/FasL signaling pathway in the resorption of lumbar intervertebral disc herniation based on the theory of Qi-blood
Su Hong
Li Yue
Tang Xiaosong
Xiao Qingqing
Abstract：Lumbar disc herniation(LDH)is a common disease in orthopedics,and its pathological mechanism in-volves disc degeneration,inflammatory response and cell apoptosis.In recent years,the treatment methods of traditional Chi-nese medicine based on Qi-blood theory have shown potential in promoting the reabsorption of protrusion,and Fas/FasL sig-naling pathway,as a key pathway to regulate cell apoptosis,may be related to the biological effects of Qi-blood theory.In this paper,by integrating the Qi-blood theory and modem molecular biology mechanism,we explore the role of Fas/FasL signaling pathway in the resorption of lumbar disc herniation,and provide experimental and theoretical basis for the prevention and treatment of LDH.
Keywords：Lumbar disc herniationThe disc was resorbedQi-blood theoryFas/FasL signaling pathway
Publication Date：2025-12-18
Online Publishing Date：2026-01-08(First online date of this platform, not the publication date of the document)
Pages：5( 1527-1531 )