Efficacy,immune function,and quality of life of patients with obstructive sleep apnea hypopnea syndrome treated with multi-plane low-temperature plasma radiofrequency ablation
Liu Xing
Ning Bo
Liu Chen
Li Huachao
Wang Chi
Abstract：Objective To explore the clinical efficacy,immune function and quality of life of patients with obstruc-tive sleep apnea hypopnea syndrome(OSAHS)after multiplanar low temperature plasma radiofrequency ablation(LTPRA).Methods A total of 120 OSAHS patients admitted to the Otolaryngology Department of Xincheng Branch of Xuzhou Cen-tral Hospital from January 2020 to January 2024 were selected as the study objects,and were divided into control group(62 cases)and observation group(58 cases)according to random number table method.The control group was treated with plasma-assisted modified uvulopalatopharyngoplasty(H-UPPP),and the observation group was treated with multiplane(LT-PRA).The clinical efficacy,related symptoms,immune function and quality of life before and after treatment were compared between the two groups.Results The total effective rate of observation group was higher than that of control group(9828％vs.80.65％,x2=4.550,P＜0.001).Compared with before treatment,sleep apnea hypopnea index(AHI)decreased and minimum blood oxygen saturation(LSAT)increased in OSAHS patients in 2 groups 3 days after surgery,and the de-crease and increase were more significant in the observation group(t=4.931,P＜0.001;t=6.330,P＜0.001).At 3 days after surgery,CD4+T lymphocytes and CD4+/CD8+decreased and CD8+T lymphocytes increased in patients with OSAHS in the 2 groups,and the increases of CD4+T lymphocytes,CD4+/CD8+and CD8+T lymphocytes decreased in the obser-vation group were greater than those in the control group(t=6.993;P＜0.001;t=2.955,P=0.004;t=9.879,P＜0.001).At 6 months after surgery,the scores of sleep apnea Quality of life index(SAQLI)of patients with OSAHS in both groups were higher than those before surgery,and the SAQLI scores in the observation group were higher than those in the control group(t=9.877,P＜0.001).Conclusion Multiplanar LTPRA can effectively improve the immunity and quality of life of OS-AHS patients,and enhance the clinical efficacy.
Keywords：Obstructive sleep apnea hypopnea syndromePlasma-assisted modified uvulopalatopharyngoplastyMulti-plane low-temperature plasma radiofrequency ablationTherapeutic effect
Publication Date：2025-01-17
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)