The predictive value of platelet-to-lymphocyte ratio combined with thromboelastography for postoperative lower ex-tremity deep venous thrombosis in patients with spontaneous intracerebral hemorrhage
Gong Yanan
Zamire Kuer-ban
Wang Liang
Jiang Shanshi
Su Na
Abstract：Objective Exploring the predictive value of platelet-to-lymphocyte ratio(PLR)combined with throm-boelastography(TEG)for postoperative deep vein thrombosis(LDVTE)in patients with spontaneous intracerebral hemor-rhage.Methods The clinical data of 83 patients with spontaneous intracerebral hemorrhage admitted to the Department of Neurology of the First Affiliated Hospital of Xinjiang Medical University from June 2020 to June 2023 were continuously se-lected.According to the occurrence of LDVTE,the patients were divided into thrombosis group(n=19)and non-thrombo-sis group(n=64).PLR values and TEG data were compared and analyzed.The correlation between PLR and TEG related in-dicators was analyzed.The receiver operating curve(AUC)of PLR,TEG and their combination was drawn and the predictive value of each index was evaluated.Results The PLR value,α Angle and MA value in the thrombosis group were signifi-cantly higher than those in the non-thrombosis group(t/P=6225/＜0.001,4290/＜0.001,3.596/＜0.001),K value and R val-ue were significantly lower than those of non-thrombosis group(t/P=3.847/＜0.001,3 281/0.002);PLR was positively corre-lated with α Angle and MA(r/P=0.402/＜0.001,0.624/＜0.001).And negatively correlated with K value(r/P=-0320/0.003).There was no significant correlation with R value(r/P=-0.104/0.349).The AUC of PLR,α Angle,MA value,K value,R value and the combination of the five factors to predict LDVTE after surgery were 0.789,0.782,0.792,0.795,0.737,0.919,respectively,and the combination of the five factors was significantly better than their individual prediction efficacy(Z/P=-2.627/0.009,-3.007/0.002,-1.999/0.046,-2.092/0.036,-3.256/0.001).Conclusion PLR and TEG are both related to LDVTE in patients after cerebral hemorrhage surgery,which can be used as reference indicators to predict the occurrence of LDVTE.PLR combined with TEG has a higher predictive value.
Keywords：Spontaneous intracerebral hemorrhageDeep venous thrombosis of the lower extremityPlatelets to lymphocyte ratioThrombus elastic figure
Publication Date：2024-08-18
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 908-912 )