Analysis of influencing factors of neonatal adverse events in pregnant women with gestational diabetes mellitus
Shan Hongyu
Zheng Xiuli
Zheng Rong
Wang Yongjun
Abstract：Objective To analyze the effect of glycated albumin(GA)level on neonatal adverse events in pregnant women with gestational diabetes mellitus(GDM).Methods The data of 360 pregnant women with GDM who delivered at full term in the Obstetric Department of Beijing Jishuitan Hospital from January 2021 to July 2022 were retrospectively ana-lyzed.They were divided into a group with neonatal adverse events(case group,60 cases)and a group without neonatal adverse events(control group,300 cases).The pregnancy data of the two groups were compared,and the regression equa-tion was established using binary logistic regression analysis for the possible influencing factors screened by univariate analysis.Results The level of GA at the end of pregnancy was higher than that of control group(t=2324,P=0.020),the pre-pregnancy body mass index(BMI)of the case group was higher than that of the control group(t=2344,P=0.019),the fasting blood glucose at the end of pregnancy was higher than that of the control group(4.6±0.5 vs 4.5±0.5,t=2518,P=0.012),and the rate of cesarean section was higher than that of the control group(x2=5.361,P=0.021).Binary logistic re-gression equation was established,and GA[OR(95％CI)=1338(1.070-1.672)]was an independent risk factor for neonatal adverse events(P=0.011).Conclusion GA level at the end of pregnancy of GDM pregnant women is correlated with the occurrence of neonatal adverse events,and the value of this index should be attached importance in clinical work.
Keywords：Gestational diabetes mellitusNewborn adverse eventsGlycated albuminBlood glucoseInfluencing factors
Publication Date：2024-07-18
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 819-822 )