Effects of combined use of Xuebijing and CVVH on the organ function and levels of inflammatory factors in elderly patients with multiple organ dysfunction syndrome
DENG Zeng
CHEN Wei
HAN Dong
HUANG Wei
Abstract：Objective To investigate the effects of combined use of Xuebijing and CVVH on PLT,TBil and Cr in elderly patients with multiple organ dysfunction syndrome.Methods Ninety-four cases of elderly patients with multiple organ dysfunction syndrome were selected,which were treated in hospital ICU hospitalization from March 2013 to March 2017,and they were divided into the observation group (47 cases) and control group (47 cases).The patients of two groups were all treated with conventional comprehensive treatment.The patients of control group were treated with CVVH (blood flow rate 200 ml/min,ultrafiltration volume 150-300 ml/min,replacement fluid flow 3 000 ml/h,continuous treatment for 1-4d).Based on control group,the patients of observation group were treated with Xuebijing injection (intravenous infusion of 100 ml times,3 times / d,treatment for 7d).Compare the clinical efficacy,ventilator support time and ICU hospital stay and changes of the levels of SCr,BUN,IL-1β,IL-10,TNF-α,TBil,PLT,PaO2,PaO2/FiO2,APACHE Ⅱ scores of two groups.Results After the appropriate treatment,the total effective rate of the observation group was 91.5％,which was significantly higher than 74.5％ of the control group (x2 =4.821,P =0.028);In terms of ventilator support time,ICU hospitalization time,PLT and APACHEⅡscore,the performance of the observation group was significantly better than the control group (P ＜ 0.05);The TBil,PaO2,PaO2/FiO2 of the two groups were significantly improved than before,and the patients in the observation group improved more significantly (P ＜ 0.05);The SCr,BUN of the two groups were significantly decreased than before,and the patients in the observation group decreased more significantly (P ＜ 0.05);The IL-1β,IL-10,TNF-α of the two groups were significantly decreased than before,and the patients in the observation group decreased more significantly (P ＜ 0.05).Conclusion Combined use of Xuebijing and CVVH in the treatment of elderly patients with multiple organ dysfunction syndrome can get the exact effect,significantly improve the organ function and prognosis,which makes it worthy of clinical application.
Keywords：Multiple organ dysfunction syndromeContinuous veno-venous hemofiltrationXuebijingQrgan functionInflammatory foctors
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 51-54 )