Patients with anti-GABA B receptor encephalitis: 5 cases report and review
JIANG Ying
LUO Changju
Abstract：Objective To discuss the clinic features of newly diagnosed anti-GABA B receptor encephalitis.Methods A retrospective analysis from May 2015 to February 2017,the characteristics and effect of treatment of 5 cases of cerebrospinal fluid and serum anti GABA BR antibody positive patients in the First Affiliated Hospital of Third Military Medical University,clinical manifestations,cerebrospinal fluid,EEG and imaging findings were analyzed.Results Five cases with anti-GABA B receptor antibody presented a subacute onset,2 combined with fever.All attack by epileptic seizure.In three of the five patients,clinical seizures were the initial symptom,two were memory deficit.Long-term EEG showed abnormal.There were hyper-intensive signal in T2/FLAIR in all patient' s limbic system.Two patients had additional autoimmune antibody in serum and cerebrospinal fluid (CSF).1 patient underwent CT/PET CT.Patients received immune regulation therapy got better outcome.Conclusion Anti-GABA B receptor encephalitis with the initial symptoms showed epilepsy can be treated.Immunomodulating therapy may be helpful to those patients.
Keywords：Anti-GABA B receptor encephalitisLimbic encephalitisAutoimmune encephalitisEpilepsy
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1149-1151 )