Risk factors of ovarian metastasis and feasibility of ovarian preservation in endometrial adenocarcinoma
ZHAO Jiao
WANG Xiaobin
TONG Xiaojing
ZHANG Yuhua
MU Peng
Abstract：Objective To analyze the clinical characteristics and risk factors of ovarian metastasis in endometrial cancer patients,explore the feasibility of ovarian preservation.Methods A retrospective analysis of 508 patients surgically staged for endometrial adenocarcinoma from January 2012 to December 2016 was performed.Collect the clinical data,and analyze the risk factors of ovarian metastasis.Results Among 508 patients,ovarian metastasis occurred in 34 patients,the incidence rate was 6.69％ (34/508).Age,menopause or not,and tumor location were not correlated with ovarian metastasis (P ＞ 0.05).The degree of tumor differentiation,depth of myometrial invasion,tumor size (≥ 2 cm),cervical invasion,lymphovascular space invasion (LVSI),pelvic and para-aortic lymph node metastasis,positive ascites cells,and positive CA125 were correlated with ovarian metastasis (P ＜ 0.05).Logistic analysis showed that lymphovascular space invasion (LVSI),pelvic and para-aortic lymph node metastasis,positive ascites cells,and positive CA125 were independent risk factors of ovarian metastasis (P ＜ 0.05).Conclusion The incidence rate of ovarian metastasis in patients with early endometrial adenocarcinoma is low,ovarian preservation is feasible;lymphovascular space invasion (LVSI),pelvic and para-aortic lymph node metastasis,positive ascites cells,and positive CA125 are independent risk factors of ovarian metastasis.
Keywords：Endometrial adenocarcinomaOvaryRisk factorOvarian preservation
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1116-1119 )