Analysis the risk factors of sepsis in patients with liver cirrhosis
WANG Dongxu
ZHU Hongbin
ZHANG Jing
Ma Donghong
Xue Minmin
Abstract：Objective To investigate the risk factors of sepsis in patients with liver cirrhosis.Methods One hundred and seventy-five patients with post hepatitis HBV cirrhosis diagnosed from January 2011 to November 2016 admitted to the digestive department of No.254 Hospital of PLA,12 cases were rejeted due to incomplete data,other 163 cases were collected as the study subjects,44 cases complicated with sepsis as sepsis group,119 cases without sepsis as non-sepsis group.The risk factors of sepsis in patients with liver cirrhosis were analyzed by logistic regression using age, sex, invasive operation history in the last 2 weeks, proton pump inhibitor, platelet count, white blood cell,neutrophils,highly sensitive C reactive protein,procalcitonin,albumin,liver hardness, Child-Turcotte-Pugh,model for end stage liver disease (MELD) scores as potential risk factors.Results Univariate analysis showed that MELD scores, white blood cell,neutrophils,highly sensitive C reactive protein,invasive operation history in the last 2 weeks, proton pump inhibitor, platelet count, MELD scores were possible variables for sepsis in patients with liver cirrhosis.After multivariate analysis, highly sensitive C reactive protein and invasive operation history in the last 2 weeks were the risk factors of sepsis in cirrhotic patients.Conclusion For patients with cirrhosis, we should pay great attention to the changes of highly sensitive C reactive protein, and try to avoid invasive procedure, which are the risk factors of sepsis in patients with liver cirrhosis.
Keywords：Liver cirrhosisSepsisInvasive procedureHigh sensitive C reactive proteinRisk factor
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 907-910 )