Correlation of hypertensive renal damage and urinary osmotic pressure, hypertension and the course of disease in high altitude area
GAO Yingying
XU Shanshan
YANG Qi
GAO Qin
ZHU Dan
WANG Xiaorong
Abstract：Objective To analyze the correlation between renal damage and urinary osmolality,hypertension grade and course of disease in high altitude area.Methods From March 2010 to December 2014,in cardiovascular disease hospital of Qinghai Province,172 cases of arrhythmia patients with hypertension in high altitude region enrolled as the research object,of which 79 cases of hypertensive renal damage(observation group),93 patients with hypertension(control group),urine osmotic pressure,different grade of hypertension and course of 2 group were observed.Results In the control group,the osmotic pressure of water,urinary albumin,urine protein and urine 24h were lower than the average in the observation group(P<0.05);the higher the grade of hypertension,the incidence of hypertensive renal damage was greater,there was a positive correlation between them(x2=33.083,P=0.000),and the renal damage of hypertension and high blood pressure showed no correlation(x2=1.190,P=0.755);the Logistic regression analysis showed that the renal damage of hypertension related factors of urinary osmotic pressure(OR=4.132,95％CI 1.234 to 16.724,P=0.002)and hypertension grade(OR=2.994,95％CI 1.111 to 17.258,P=0.003),and has nothing to do with the duration of hypertension(OR=1.112,95％CI 0.234 to 0.781,P=0.089).Conclusion There is a positive correlation between hypertensive renal damage and urinary osmotic pressure and hypertension in high altitude area,which is not related to the course of hypertension.
Keywords：High altitude areaHypertensive renal damageUrinary osmotic pressureHypertension classificationCourse of diseaseCorrelation
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 773-775 )