Study on the accuracy of blood flow sensitive stationary phase and stationary free sequence in the infragenual arteries
LIU Jiayi
ZHANG Nan
LUO Nan
LIU Dongting
WANG Wenchuan
LI Yu
WEN Zhaoying
FAN Zhanming
Abstract：Objective To evaluate the diagnostic accuracy of flow-sensitive dephasing-prepared steady-state free precession for imaging infragenual arteries relative to Ultrasound, CE-MRA and DSA.Methods A series of 16 consecutive patients with peripheral arterial disease (PAD) underwent a combined peripheral MRA protocol consisting of FSD-MRA for the calves and large field-of-view CE-MRA.All patients accept ultrasound before MRA.DSA was performed on all patients within 1 week of the MR angiographies.Image quality and degree of stenosis was assessed by two readers with more than 5 years of vascular imaging experience.Inter-observer agreement was determined using kappa statistics.Receiver operating characteristic (ROC) curve analysis determined the diagnostic value of FSD-MRA, CE-MRA, CE-MRA combined with FSD-MRA (CE+FSD MRA) and ultrasound in predicting vascular stenosis.Results Inter-reader agreement was excellent for both FSD-MRA and CE-MRA.Both of FSD-MRA and CE-MRA carry a stenosis overestimation risk relative to DSA standard.Stenosis was underestimated in ultrasound.With DSA as the reference standard, ROC curve analysis showed that the area under the curve was largest for CE+FSD MRA(ROC=0.929)and smallest for ultrasound(ROC=0.860).The greatest sensitivity and specificity were obtained when a cut-off stenosis score of 2 was used.Conclusion In patients with severe PAD, FSD-MRA provides good-quality diagnostic images without a contrast agent and is a good supplement for CE-MRA.CE+FSD MRA can improve the accuracy of vascular stenosis diagnosis.
Keywords：MR-angiographyFlow-sensitive dephasing phase-prepared steady-state free precessionUltrasoundDigital sbstraction angiographyLower limb artery stenosis
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 600-604 )