Correlations of serum high sensitivity C reactive protein and serum amyloid A concentrations after PCI with in-stent restenosis
YANG Liwen
XIA Hao
TIAN Guowei
ZHENG Yage
Abstract：Objective To explore the associations of serum high sensitivity C reactive protein (hs-CRP) and serum amyloid A (SAA) concentrations after PCI with in-stent restenosis (ISR).Methods One hundred and twenty-one patients who were diagnosed CHD by coronary angiography and underwent PCI treatment from April 2015 to April 2016 in Renmin Hospital of Wuhan University were enrolled.We evaluated every patient's coronary lesions according to Gensini score criteria.Patients who were followed up 8 months after PCI were divided into ISR group (34 cases) or NISR group (87 cases) according to whether combined with ISR (The ISR was defined as the reduction of lumen diameter≥50%).The basic clinical data, laboratory results and coronary lesions of the patients in two groups were compared.Results There were no significant difference in the basic clinical data, location, number and degree of coronary lesion between the two groups (P>0.05).Compared with NISR group, ISR group was significantly higher in level of hs-CRP and SAA(t=3.825,3.723,P<0.05), but other laboratory results have no significant difference between the two groups (P>0.05).The logistic analysis showed that a relatively higher level of hs-CRP and SAA (OR=1.221,1.058,P<0.05) may be the independent risk factors of ISR.Conclusion The higher the level of hs-CRP and SAA after PCI, the greater the risk of ISR.The high level of hs-CRP and SAA may be the independent risk factors of ISR.
Keywords：Coronary heart diseasePercutaneous coronary interventionHigh sensitivity C reactive proteinSerum amyloid AIn-stent restenosis
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 541-544,549 )